Rachel and Talia Fontenot are sisters born into brutal, rural poverty of southeastern Louisiana in the 1960s.

Raised with one another until tragic circumstances intervene and they are separated. Talia disappearing into a life of drugs and petty crime, Rachel fleeing to New Orleans. It is now present day and Talia has been missing for many years. Rachel in New Orleans is living what appears to be the perfect life, but underneath she is struggling with constant anxiety, prescription drug abuse and tremendous grief over the loss of her missing sister, as well as her oldest son to an accident several years earlier.

One night, she receives a call from a nurse she's not heard from since Hurricane Katrina. The information she is given sets in motion a series of events that will unravel. Rachel's life forced her to examine her past choices and takes her on a psychologically arduous journey to save her sister.